science vs. Nature

 In the story Georgina herself and her birthmark represent the power of nature. Alymer represents science and its imperfection. Georgina's beautiful voice restores Alymer's good mood which would be nature proving its power to science. Alymer however tried to correct Georgina's birthmark and the result of using science to correct nature was death and unhappiness. This article refers to how science is evil and nature is perfection and beauty.  http://www.sparknotes.com/short-stories/the-birthmark/themes.html